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Updated: Feb 6, 2026

Identification of Coding and Non-coding RNA Classes Expressed in Swine Whole Blood

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Coding and non-coding RNA sequencing during Thalassiosira gravida resting cell formation.

Rosa Maria Sepe^1,2, Ida Orefice³, Marco Di Marsico⁴

¹Ecosustainable Marine Biotechnology Department, Stazione Zoologica Anton Dohrn, Via Ammiraglio Ferdinando Acton 55, Giardini Molosiglio, 80133, Naples, Italy.

Scientific Data

|February 4, 2026

Summary

This study reveals molecular insights into diatom resting cell formation. We sequenced RNA during nitrogen depletion in Thalassiosira gravida to understand the switch between growth and quiescence.

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Area of Science:

Marine biology
Microalgal research
Molecular biology

Background:

Diatoms are vital unicellular microalgae in aquatic ecosystems.
They produce bioactive compounds and have complex life cycles, including a quiescent state for survival.
Molecular mechanisms of the growth-quiescence transition are poorly understood.

Purpose of the Study:

To investigate the molecular mechanisms governing the transition to the quiescent state in diatoms.
To provide novel omics data on resting cell formation.

Main Methods:

Induction of resting cell formation via nitrogen depletion in Thalassiosira gravida.
Multi-timepoint sequencing of coding and non-coding RNAs.

Main Results:

Generated comprehensive RNA sequencing data during resting cell formation.
Identified molecular changes associated with the initiation and maintenance of quiescence.

Conclusions:

This study offers the first multi-timepoint RNA sequencing dataset for diatom resting cell formation.
The data will facilitate further research into the molecular pathways regulating diatom quiescence and survival.