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Updated: Feb 6, 2026

Production of Chemicals by Klebsiella pneumoniae Using Bamboo Hydrolysate as Feedstock
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Association of Biliary Source Klebsiella pneumoniae Pyogenic Liver Abscess With Colon Adenocarcinoma: A Case Report

Dongmin Shin1, Sameer Kandhi1, Franklin Sosa1

  • 1Division of Gastroenterology, BronxCare Health System, Bronx, New York, USA, bronxcare.org.

Case Reports in Gastrointestinal Medicine
|February 5, 2026
PubMed
Abstract

Insights

Klebsiella pneumoniae liver abscesses can indicate colorectal cancer, even with a biliary source. Early colonoscopy in these cases aids in detecting occult malignancy for better patient outcomes.

Area of Science:

  • Hepatology
  • Gastroenterology
  • Infectious Diseases

Background:

  • Pyogenic liver abscesses (PLAs) often stem from biliary tract infections or hematogenous spread.
  • Klebsiella pneumoniae is a common PLA pathogen linked to gastrointestinal malignancies, especially colorectal cancer.
  • Malignancy screening is standard for cryptogenic K. pneumoniae PLAs, but less defined when a biliary source is evident.

Purpose of the Study:

  • To highlight the significance of colorectal cancer screening in patients with K. pneumoniae PLA, even with a concurrent biliary source.
  • To emphasize the potential for early diagnosis of occult malignancy through endoscopic evaluation.

Main Methods:

  • Case report of a 76-year-old male presenting with symptoms suggestive of liver abscess and cholecystitis.
  • Percutaneous drainage of the liver abscess with K. pneumoniae identification.
  • Colonoscopy performed due to the pathogen's association with colorectal neoplasia, despite apparent biliary source.

Main Results:

  • Imaging revealed a pericholecystic liver abscess and acute cholecystitis.
  • K. pneumoniae was isolated from the abscess.
  • Colonoscopy identified multiple large laterally spreading tumors, including invasive adenocarcinoma of the ascending colon.

Conclusions:

  • K. pneumoniae PLA warrants consideration for colorectal cancer screening, irrespective of an identified biliary source.
  • Prompt endoscopic evaluation in these patients can lead to the timely diagnosis of underlying malignancy.
  • Early detection of occult gastrointestinal cancers can significantly alter clinical management and improve prognoses.
Keywords:
Klebsiella pneumoniaecolonic polypcolorectal cancerliver abscesspyogenic

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