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Drug-Induced Immune Thrombocytopenia Secondary to Trimethoprim-Sulfamethoxazole
Christopher Cimperman1,2, Elysha Whitesel2,3, Amy Ray2,4
1Department of Medicine, Division of Palliative Care, MetroHealth Medical Center, Cleveland, Ohio, USA, metrohealth.org.
Abstract:
We report the case of a 55-year-old male with AIDS who developed severe thrombocytopenia following initiation of trimethoprim-sulfamethoxazole. Despite drug discontinuation and supportive measures, thrombocytopenia persisted, leading to the patient's death. This case highlights the complexities of drug-induced immune thrombocytopenia in immunocompromised patients and emphasizes the risks associated with trimethoprim-sulfamethoxazole.
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