Related Experiment Video
Updated: Feb 6, 2026
Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
Published on: July 7, 2023
Effect of multidisciplinary closed-loop care on pregnancy outcomes in anxiety and depression
Tian-Tian Shen1, Ya-Juan Zhang2, Qiu-Xia Xie3
1Department of Obstetrics and Gynecology, Songjiang Maternal and Child Health Hospital of Shanghai, Shanghai 201620, China.
Background:
Perinatal anxiety and depression are prevalent conditions associated with significant health risks. Investigating the efficacy of a multidisciplinary approach combined with a closed-loop psychological intervention is essential for improving related outcomes.
Aim:
To evaluate the clinical value of a multidisciplinary closed-loop intervention in improving pregnancy outcomes and promoting postpartum recovery in pregnant women with anxiety and depression.
Methods:
We conducted a randomized controlled trial involving 240 pregnant women with anxiety and depressive symptoms who received regular prenatal care at Shanghai Songjiang Maternal and Child Health Hospital between January 2024 and January 2025. Participants were randomized to an intervention group (multidisciplinary closed-loop intervention) or a control group (routine care). Delivery outcomes, maternal and neonatal complications, and postpartum pelvic floor function were compared.
Results:
The intervention group exhibited significantly lower rates of cesarean section (31.7% vs 44.2%, P < 0.05), adverse maternal outcomes (15% vs 32.5%, P < 0.01), and adverse neonatal outcomes (6.7% vs 15.8%, P < 0.05). Additionally, the intervention group demonstrated higher rates of normal labor progression (96.3% vs 86.5%, P < 0.05) and intact perineum (50.0% vs 32.8%, P < 0.05), alongside superior pelvic floor muscle recovery.
Conclusion:
This integrated multidisciplinary closed-loop intervention model effectively improves maternal and infant outcomes and enhanced postpartum recovery in women experiencing perinatal anxiety and depression.
Related Concept Videos
01:17Open and closed-loop control systems
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
01:05Long-term Depression
01:18Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
03:12Freezing Point Depression and Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
01:28Depressants
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
01:30Generalized Anxiety Disorder