Clinicopathological Profile and Recurrence Pattern of Granular Cell Tumor Cases in a Tertiary Center in Central...

Granular cell tumors (GCT) are rare, mostly benign tumors originating from the neural sheath, with a higher prevalence in the head and neck region. This research aimed to characterize the clinical and pathological patterns of GCT presented to a tertiary care center in central Kerala, India, and to evaluate recurrence rates in this cohort over a 54.4-month follow-up period. Over the span of 8 years, 36 cases of granular cell tumors were diagnosed, with 52.8% of the patients being female. The mean age at presentation was 43 years (SD ± 18.1 years). The head and neck were the most common region of occurrence (43.75%), with the tongue being the most frequently affected site. The mean tumor size was 1.49 cm (SD ± 0.78 cm). All cases were diagnosed as benign GCTs. Among the 14 patients who were followed up, no recurrences were observed, regardless of whether their surgical margins were positive or negative.