Related Experiment Video
Updated: Feb 7, 2026
![An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F66708.jpg&w=3840&q=50)
An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use
Published on: May 24, 2024
FAPI Uptake in Avascular Necrosis of the Talus
Amin Saber Tanha1, Nasrin Raeisi, Farivash Karamian
1Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract:
We present a case of metastatic castration-resistant prostate cancer (mCRPC) with prior hepatic involvement who ultimately received 177 Lu-PSMA therapy. During the posttreatment scan following the third cycle, atypical uptake was observed in the left ankle, which was also evident as FAPI uptake on the 68 Ga-FAPI-46 PET/CT performed for restaging, and was subsequently confirmed as avascular necrosis through MRI correlation. This case illustrates the false-positive uptake of 177 Lu-PSMA-617 and 68 Ga-FAPI-46 in avascular necrosis of the talus.
More Related Videos
Related Concept Videos
Necrosis
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
Drugs Affecting Neurotransmitter Release or Uptake
Antibiotic Selection
Responses to Salt Stress
Electron Transport Chains
The ETC is comprised of...
Receptor-mediated Endocytosis

