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Updated: May 5, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
[Arterial embolism in a patient's feet]
Aimee E B Kockelbergh1, M E Baarsma1, Jacob W Bosma1,2
1Zaans Medisch Centrum, afd. Interne Geneeskunde, Zaandam.
None:
A 69-year-old woman presented with progressive gangrene affecting the toes of both feet. Laboratory investigations showed marked thrombocytosis (800 x 109/l). A positive JAK2V617F-mutation confirmed essential thrombocytosis as the underlying cause of the gangrene. With thrombocyte-lowering therapy, platelet counts normalized and the gangrene showed no further progression.
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