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Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
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Residual stresses reside in a structure even after removing the original stress inducer. This phenomenon often arises from varied plastic deformations across different parts of a structure. Consider a rod stretched beyond its yield point. It will not regain its original length due to permanent deformation. Even after load removal, the rod does not entirely lose stress because of uneven plastic deformations, resulting in residual stresses. The computation of these stresses in structures is...
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Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
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In materials that exhibit elastic and plastic behavior, known as elastoplastic materials, residual stresses can accumulate when these materials experience plastic deformation. This deformation arises from either high levels of shearing stress or significant strains. Residual stresses are internal stresses that persist within a material after removing the external force causing deformation. This phenomenon is demonstrated when observing the behavior of a shaft under torque; notably, the...
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In the study of elastoplastic members subjected to bending moments, understanding the loading and unloading phases is crucial for assessing material behavior and structural integrity. During the loading phase, as the bending moment increases, the material initially responds elastically, adhering to Hooke's Law, where stress is directly proportional to strain. When the load exceeds the yield strength, plastic deformation occurs, resulting in permanent strain and deformation that remains even...
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Residual Left Atrial Appendage After Incomplete Surgical Closure.

Anish K Desai1, Jeffrey Chidester1, Olivia Ondigi1

  • 1Division of Cardiovascular Medicine, University of Virginia, Charlottesville, Virginia, USA.

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|February 5, 2026
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Summary
This summary is machine-generated.

Incomplete surgical left atrial appendage occlusion (LAAO) requires careful management. Transcatheter LAAO and medical strategies can address residual LAA challenges, with imaging guiding treatment decisions.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Device Technology

Background:

Keywords:
anticoagulationatrial fibrillationcardiovascular diseasecomputed tomographyelectrophysiologyhemorrhageimagingintravascular ultrasoundoccluderthrombus

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  • Atrial fibrillation (AF) necessitates anticoagulation to prevent stroke, but treatment intolerance is common.
  • Surgical left atrial appendage occlusion (LAAO) provides an alternative stroke prevention strategy for AF patients.
  • Incomplete closure after surgical LAAO can lead to residual left atrial appendage (LAA) patency, posing management difficulties.