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Updated: Feb 7, 2026

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Distances and charges along the Orai1 nexus-TM3 interface control STIM1 binding and pore opening

Julia Söllner1, Magdalena Prantl1, Hadil Najjar1

  • 1Institute of Biophysics, JKU Life Science Center, Johannes Kepler University Linz, Gruberstraße 40, 4020 Linz, Austria.

Cell Reports
|February 5, 2026
PubMed

Keywords:
CP: cell biologyCRAC channelOrai1STIM1chemical crosslinking UAAconformational dynamicscysteine crosslinkinggenetic code expansionnexus-TM3 interfacephotocrosslinking UAAunnatural amino acids

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