Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

5.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

424
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
424
The Central Dogma01:25

The Central Dogma

139.9K
Overview
139.9K
Clinical Trials01:16

Clinical Trials

10.8K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.8K
Measures of Central Tendency02:16

Measures of Central Tendency

21.3K
The "center" of a data set is also a way of describing location. The two most widely used measures of the "center" of the data are the mean (average) and the median. The words "mean" and "average" are often used interchangeably. The substitution of one word for the other is common practice. The technical term is "arithmetic mean" and "average" is technically a center location. However, in practice among non-statisticians,...
21.3K
Random Error01:04

Random Error

9.8K
Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...
9.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Care of Infants and Children with Tracheostomies: An Official American Thoracic Society Clinical Practice Guideline.

American journal of respiratory and critical care medicine·2025
Same author

Do young adults complete health care proxies before anesthesia?

Health care transitions·2024
Same author

Continuity Strategies for Long-Stay PICU Patients: Consensus Statements From the Lucile Packard Foundation PICU Continuity Panel.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·2024
Same author

Academic Half Day Improves Resident Perception of Education Without Compromising Patient Safety.

Academic pediatrics·2024
Same author

The more you know: Insights from integrated pre-visit surveys in a pediatric environmental health center.

International public health journal·2024
Same author

Parental Adverse Childhood Experiences and Post-PICU Stress in Children and Parents.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·2023

Related Experiment Video

Updated: Feb 7, 2026

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
03:53

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

2.9K

A Visual Tool for Central Line Consent: A Randomized Feasibility Trial.

Matthew C Spence1,2, Jeffrey D Edwards1

  • 1Division of Pediatric Critical Care and Hospital Medicine, Columbia University Irving Medical Center, New York-Presbyterian Morgan Stanley Children's Hospital, New York, New York.

Hospital Pediatrics
|February 5, 2026
PubMed
Summary

This pilot study assessed a new visual tool for central venous access consent. While feasible and acceptable to parents, it did not significantly reduce anxiety or improve decisional comfort.

More Related Videos

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.6K
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.2K

Related Experiment Videos

Last Updated: Feb 7, 2026

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
03:53

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management

Published on: March 15, 2024

2.9K
Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.6K
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.2K

Area of Science:

  • Pediatric Intensive Care
  • Clinical Trial Feasibility
  • Medical Device Evaluation

Background:

  • Procedural consent for central venous access in pediatric intensive care units (PICUs) can cause anxiety for surrogate decision-makers.
  • Assessing the impact of novel tools on parental anxiety and decisional comfort is crucial for improving the consent process.

Purpose of the Study:

  • To determine the feasibility of a clinical trial evaluating a novel central venous access visual tool.
  • To assess the tool's impact on surrogate decision-makers' anxiety and decisional comfort during procedural consent.

Main Methods:

  • A single-site, randomized pilot study involving parents of children requiring central venous access.
  • Parents were randomized to receive consent with or without the visual tool, with anxiety and decisional comfort measured using validated scales.
  • Feasibility was assessed by enrollment, retention, randomization, and parental acceptability.

Main Results:

  • Twenty-eight parents were enrolled and randomized, demonstrating good feasibility for enrollment and randomization.
  • Parents found the visual tool and study procedures highly acceptable.
  • No statistically significant differences were observed in parental state anxiety or decisional comfort between groups.

Conclusions:

  • The study demonstrated feasibility in terms of enrollment, retention, randomization, and parental acceptability for a clinical trial of a central venous access visual tool.
  • The tool did not show preliminary efficacy in decreasing parental anxiety or decisional discomfort.
  • Further research may be needed to refine the tool or explore its efficacy in different contexts.