Related Experiment Video
Updated: May 1, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Pilot study evaluating a clinical decision support tool: "Virtual Lipidologist HTE-DLP 3.0"
Alberto Zamora1, Cristina Soler2, Emilio Ortega3
1Unidad de Lípidos y Riesgo Vascular, Servicio de Medicina Interna, Hospital Comarcal de Blanes, Blanes, Girona, España; Grupo de Innovación en Salud Digital-CSMS, Instituto de Investigación Biomédica de Girona Dr. Josep Trueta (CREA-IDIBGI), Girona, España; Facultad de Medicina, Universidad de Girona, Girona, España; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBER-CV), Madrid, España; Associació Xarxa d'Unitats de Lípids i Arterioesclerosi de Catalunya, Sociedad Catalana de Lípidos y Arteriosclerosis (SOC XULA), Barcelona, España.
Introduction:
Clinical decision support systems can improve guideline adherence and reduce variability. HTE-DLP 3.0 (Virtual Lipidologist) provides recommendations based on scientific evidence, safety, and cost-effectiveness criteria.
Methods:
A proof-of-concept study was conducted using 10 standardized clinical cases evaluated by 9 clinicians before and after the use of the HTE-DLP 3.0. Therapeutic variability was analyzed using the Simpson Diversity Index and the kappa coefficient. Usability and user experience were assessed using the CSUQ and QoE questionnaires, together with a qualitative survey on strengths and areas for improvement.
Results:
Baseline assessment showed very significant interprofessional variability. Uniform adherence to the shared algorithmic recommendation is observed. The CSUQ showed good efficiency scores (6.40) and high satisfaction (5.42/7), with error messages and the availability of clinical support tools identified as areas for improvement. The QoE showed high scores for data security (4.71), clinical usefulness (4.57), and social impact (4.57), with learning time being the lowest-rated aspect (2.85/5).
Conclusions:
HTE-DLP 3.0 demonstrated the ability to act as a decision standardization tool based on clinical practice guidelines. Further studies in real-world clinical practice will be necessary to evaluate its clinical and cost-effectiveness impact.
Related Concept Videos
Lipid Digestion
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Atherosclerosis III: Management

