Pilot study evaluating a clinical decision support tool: "Virtual Lipidologist HTE-DLP 3.0"

Area of Science:

• Medical Informatics
• Clinical Decision Support Systems

Background:

• Clinical decision support systems (CDSS) enhance guideline adherence and reduce practice variability.
• HTE-DLP 3.0 (Virtual Lipidologist) offers evidence-based, safe, and cost-effective recommendations.

Purpose of the Study:

• To evaluate the impact of HTE-DLP 3.0 on therapeutic variability and clinician decision-making.
• To assess the usability and user experience of the HTE-DLP 3.0 system.

Main Methods:

• A proof-of-concept study involved 9 clinicians evaluating 10 standardized cases before and after HTE-DLP 3.0 use.
• Therapeutic variability was quantified using the Simpson Diversity Index and kappa coefficient.
• Usability and user experience were assessed via CSUQ, QoE questionnaires, and a qualitative survey.

Main Results:

• Baseline analysis revealed significant interprofessional variability, which was reduced to uniform adherence post-HTE-DLP 3.0 implementation.
• The CSUQ indicated good efficiency (6.40) and high satisfaction (5.42/7), with suggestions for improving error messages and support tools.
• QoE scores were high for data security (4.71), clinical usefulness (4.57), and social impact (4.57); learning time received the lowest score (2.85/5).

Conclusions:

• HTE-DLP 3.0 effectively standardized clinical decisions according to practice guidelines.
• Further real-world clinical practice studies are required to determine its clinical and cost-effectiveness.