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Mechanistic insights into postoperative delirium using untargeted high-throughput proteomics in elderly patients - a

Mario Lamping1, Maria Heinrich1,2, Vadim Farztdinov3

  • 1Department of Anaesthesiology and Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany.

Scientific Reports
|February 5, 2026
PubMed
Summary

Postoperative delirium (POD) in elderly patients is linked to immune and complement system pathways. A novel protein signature may help identify patients at risk for this common surgical complication.

Keywords:
ClassifierDeliriumMass spectrometryPathway analysisProteomics

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