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European Working Group on Sarcopenia in Older People Algorithm: Step-by-Step Relation With Length of Hospitalization.

Elena Zoico¹, Silvia Urbani¹, Anna Giani¹

¹Division of Geriatric Medicine, Department of Medicine, University of Verona, Verona, Italy.

Journal of the American Geriatrics Society

|February 6, 2026

Summary

The European Working Group on Sarcopenia in Older People 2 (EWGSOP2) guidelines effectively identify sarcopenia in hospitalized older adults, with each diagnostic step improving prediction of adverse outcomes. Muscle strength and SARC-F scores remain valuable when body composition data is unavailable.

Keywords:

SARC‐F aging body composition dynapenia sarcopenia

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Area of Science:

Geriatric Medicine
Clinical Nutrition
Aging Research

Background:

Lack of international consensus on sarcopenia definition in hospitalized older adults.
Need to evaluate the EWGSOP2 guidelines for predicting adverse outcomes in this population.

Purpose of the Study:

To test the EWGSOP2 guidelines' predictivity for adverse clinical outcomes in hospitalized older adults.
To evaluate the step-by-step capability of EWGSOP2 in predicting unfavorable clinical events.

Main Methods:

Inclusion of 604 hospitalized patients aged 65-99 years.
Application of EWGSOP2 guidelines for sarcopenia diagnosis.
Assessment of clinical outcomes including length of hospital stay, fall risk, and quality of life.

Main Results:

Sarcopenia prevalence was 22% among hospitalized older adults.
Shorter hospital stays were observed in non-sarcopenic patients compared to dynapenic and sarcopenic subjects.
Each step of the EWGSOP2 algorithm showed a progressively greater association with adverse clinical outcomes.

Conclusions:

The EWGSOP2 algorithm is a valid tool for assessing sarcopenia in hospitalized older patients.
Each diagnostic step of EWGSOP2 enhances its predictivity for adverse outcomes.
SARC-F and muscle strength are valuable predictors of negative outcomes when body composition data is absent.