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The Effect of Binaural Sound on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A
Jung-Bin Park1, Ji-Hyun Lee1, Yoon Jung Kim1
1Department of Anaesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Insights
Binaural beats did not significantly reduce emergence delirium (ED) in pediatric surgery patients. However, the binaural beats group showed lower Pediatric Anesthesia Emergence Delirium (PAED) scores during recovery.
Area of Science:
- Anesthesiology
- Neuroscience
- Pediatric Surgery
Background:
- Binaural beats are known to induce brainwave entrainment and have shown potential in reducing anxiety and sedative use.
- Emergence delirium (ED) is a common complication in children after general anesthesia, particularly after strabismus surgery.
- This study investigated the efficacy of binaural beats in mitigating ED in pediatric patients.
Purpose of the Study:
- To evaluate the effect of binaural beats on the incidence of emergence delirium (ED) in children undergoing strabismus surgery.
- To assess secondary outcomes including ED severity scores and postanesthesia care unit (PACU) stay duration.
Main Methods:
- A randomized controlled trial involving 73 pediatric patients aged 2-7 years.
- Patients received either binaural beats or noise-canceled silence during general anesthesia.
- ED was assessed using the Pediatric Anesthesia Emergence Delirium (PAED) and Watcha scores.
Main Results:
- The incidence of ED did not significantly differ between the binaural beats group and the control group (38.89% vs. 54.05%).
- However, the binaural beats group exhibited significantly lower PAED scores upon arrival, at 20 minutes, and the highest score during PACU stay.
- No significant differences were observed in Watcha scores, FLACC scores, electroencephalogram band power, or PACU stay duration.
Conclusions:
- Binaural beat application during general anesthesia did not significantly reduce the incidence of emergence delirium in pediatric patients.
- Exploratory analysis suggests a potential reduction in the maximum PAED score, warranting further investigation.
- The findings indicate that while binaural beats may not prevent ED, they might alleviate its severity.
Background:
Binaural beats, which induce brainwave entrainment, have reduced anxiety and sedative use. This study evaluated the effect of binaural beats on emergence delirium (ED) in children undergoing strabismus surgery under general anesthesia.
Methods:
This randomized controlled trial included 73 pediatric patients aged 2-7 years receiving binaural beats (n = 36) or noise-canceled silence (n = 37) during general anesthesia. ED was defined as a Pediatric Anesthesia Emergence Delirium (PAED) score > 12 or Watcha score > 2. Primary outcome was the incidence of ED. Secondary outcomes included PAED, Watcha, and Faces Legs Activity Cry Consolability (FLACC) scores in the postanesthesia care unit (PACU), intraoperative electroencephalogram band power differences, and PACU stay duration.
Results:
The incidence of ED did not significantly differ between groups (38.89% vs. 54.05%; relative risk 1.39 [95% confidence interval (CI), 0.84-2.31]; p = 0.287). However, PAED scores at PACU arrival, at 20 min, and the highest score during PACU stay were significantly lower in the binaural group (median difference -1 [95% CI, -3 to 0]; p = 0.026 at arrival; -4 [95% CI, -4 to 0]; p = 0.035 at 20 min; -1 [95% CI, -3 to 0]; p = 0.048 for the highest score). Watcha and FLACC scores, band powers, and PACU stay duration did not differ significantly between groups.
Conclusions:
Binaural beat application during general anesthesia did not significantly reduce the incidence of ED. Exploratory analyses suggested a reduction in maximum PAED score, but this requires further study.
Trial Registration:
NCT05883280 (registered at http://clinicaltrials.gov (registration number, principal investigator: Jeong-Hwa Seo, registration date: May 22, 2023)).
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