Complicated Catastrophic Calcium Gluconate Extravasation: Post-Surgical Graft Calcinosis Cutis

Extravasation is a rare but serious complication of intravenous injections, particularly with irritant or vesicant drugs, which can lead to significant tissue damage. In this case report, we describe a 14-year-old boy who developed calcinosis cutis due to extravasation of calcium gluconate, resulting in extensive tissue necrosis. Although surgical debridement and grafting were performed, the patient subsequently experienced iatrogenic post-surgical graft calcinosis cutis, leading to severe hand disability. This case underscores the importance of prompt recognition and management of extravasation to prevent long-term complications.