Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Applications of Integration to Find Centers of Mass01:30

Applications of Integration to Find Centers of Mass

83
Rotational equilibrium provides a natural framework for defining the center of mass of a system. For a plank balanced on a pivot with two unequal masses, equilibrium is achieved when the net torque about the pivot is zero. Torque is defined as the product of a force and its perpendicular distance from the pivot. When the torques due to all forces cancel, the pivot coincides with the center of mass of the system.For a system composed of several discrete point masses, the center of mass lies at...
83
The Evidence for Evolution02:55

The Evidence for Evolution

48.3K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
48.3K
Convergent Evolution01:54

Convergent Evolution

33.0K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
33.0K
Social Foundations of Self II: The Generalized Other01:20

Social Foundations of Self II: The Generalized Other

267
According to George Herbert Mead, as children progress beyond the game stage, they develop a more comprehensive understanding of societal rules and norms. This cognitive and social development enables them to internalize the expectations of the broader community, refining their ability to regulate behavior.Consistent participation in organized activities is crucial in helping children recognize that their actions are not isolated but contribute to a more significant, interconnected group...
267
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

681
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
681
Theoretical Foundations of Nursing Practice01:30

Theoretical Foundations of Nursing Practice

17.5K
Theories play an essential role in organizing patient care. Theories refer to a proposed or followed belief, policy, or procedure that is the basis for action. Nursing theories are knowledge-based concepts that guide nurses' actions, influence nursing education and practice, and allow nurses to care for their patients.
Theories provide a perspective to assess patients' conditions and organize data and methods. They also assist in analyzing and interpreting information. They represent a...
17.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimated Financial Costs of Dermatology Away Rotations Across U.S. Metropolitan Regions.

Journal of the American Academy of Dermatology·2026
Same author

Systemic Glucocorticoid Immunosuppression and Survival Among Immune Checkpoint Inhibitor Recipients.

JAMA network open·2026
Same author

Impact of clinicopathological features on prognosis of thin melanomas: a retrospective cohort analysis.

The British journal of dermatology·2026
Same author

Gender differences in sun protection use and beliefs amongst outdoor athletes.

International journal of women's dermatology·2025
Same author

Effect of systemic glucocorticoid immunosuppression timing, dose, and duration on overall survival among immune checkpoint inhibitor recipients: a retrospective multicohort study.

medRxiv : the preprint server for health sciences·2025
Same author

Lessons learned from the Dermoscopy Bowl for dermatology residents.

Archives of dermatological research·2024
Same journal

MetaboNet-Bench: A Multi-modal Benchmark for Glucose Forecasting in Type 1 Diabetes.

ArXiv·2026
Same journal

A Positron Range Correction with Texture Preservation Framework in PET Imaging.

ArXiv·2026
Same journal

Automated optimization of force field parameters against ensemble-averaged measurements with Bayesian Inference of Conformational Populations.

ArXiv·2026
Same journal

Droplet Fusion as a Relaxation Process: Comparison with Shape Recovery of Newtonian and Viscoelastic Droplets.

ArXiv·2026
Same journal

Ridge-filter crosstalk in conformal proton FLASH planning: dependence on beamlet pitch and iterative mitigation.

ArXiv·2026
Same journal

Electrochemical DNA Hairpin Sensors for Differentiating Small Molecule Intercalation from Minor Groove Binding.

ArXiv·2026
See all related articles

Related Experiment Video

Updated: Feb 7, 2026

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
09:56

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

Published on: April 30, 2019

7.0K

Histopathology-centered Computational Evolution of Spatial Omics: Integration, Mapping, and Foundation Models.

Ninghui Hao, Xinxing Yang, Boshen Yan

    Arxiv
    |February 6, 2026
    PubMed
    Summary
    This summary is machine-generated.

    This survey reviews computational methods for spatial omics (SO) analysis, focusing on how hematoxylin and eosin (H&E) images are integrated with molecular data. It outlines three paradigms: integration, mapping, and foundation models, offering a roadmap for future research.

    More Related Videos

    Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
    11:52

    Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

    Published on: February 9, 2017

    6.5K
    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
    13:12

    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

    Published on: August 12, 2019

    46.5K

    Related Experiment Videos

    Last Updated: Feb 7, 2026

    Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
    09:56

    Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

    Published on: April 30, 2019

    7.0K
    Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
    11:52

    Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

    Published on: February 9, 2017

    6.5K
    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
    13:12

    Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

    Published on: August 12, 2019

    46.5K

    Area of Science:

    • Computational pathology
    • Spatial omics
    • Bioinformatics

    Background:

    • Hematoxylin and eosin (H&E) imaging is the standard for morphological assessment in pathology.
    • Spatial omics (SO) technologies provide spatially resolved molecular profiling.
    • Computational methods are increasingly integrating H&E imaging with SO data for enhanced analysis.

    Purpose of the Study:

    • To systematically review the computational evolution of SO from a histopathology-centered perspective.
    • To organize existing computational methods into three paradigms: integration, mapping, and foundation models.
    • To analyze the evolving role of H&E images in SO analysis.

    Main Methods:

    • Review of computational methods in spatial omics.
    • Categorization of methods into integration, mapping, and foundation models.
    • Analysis of H&E image roles across different computational paradigms.

    Main Results:

    • H&E images evolve from spatial context to predictive anchors and representation backbones in SO computational frameworks.
    • Three computational paradigms (integration, mapping, foundation models) are identified.
    • Practical constraints like limited paired data and resolution demands drive H&E image integration.

    Conclusions:

    • The survey provides a histopathology-centered roadmap for computational frameworks in spatial omics.
    • Actionable modeling directions and persistent gaps in data, biology, and technology are identified.
    • Future advancements require addressing challenges beyond model design.