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Laser-assisted Analgesic and Vasoconstrictive Drug Delivery During and After Fractional CO2 Resurfacing: A Novel
Iman Ali1, Roger Ceilley2, Ciaran Smythe3
1Dr. Ali is with the Department of Internal Medicine at Texas Health Presbyterian Dallas in Dallas, Texas, and the McGovern Medical School at the University of Texas Health Science Center at Houston in Houston, Texas.
Background:
Fractional carbon dioxide (CO2) laser resurfacing is an effective treatment of various dermatological conditions. Pain, erythema, and edema following fractional ablative resurfacing are key limitations to patient comfort and satisfaction.
Objective:
This study aims to describe a novel technique using laser-assisted drug delivery to administer a combination of local anesthetics and epinephrine both during and after fractional CO2 laser resurfacing, enhancing procedural anesthesia and postprocedure recovery.
Methods:
We performed an observational review of patient-reported pain scores and clinical outcomes in patients treated with application of an anesthetic spray during and after fractional CO2 laser resurfacing treatments.
Results:
Patients demonstrated an average of 68% reduction in pain scores (p<0.001) scores postapplication, with additional clinical improvements in postlaser erythema and edema.
Conclusion:
Laser-assisted drug delivery of local anesthetics and epinephrine after fractional ablative resurfacing appears to offer a simple, low-cost adjunct for improving patient experience and recovery. Further investigation is warranted.
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