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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
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Association Between Conflict of Interest and Published Position on Bioabsorbable Nasal Valve Implants
Lauren Gardiner1, Elizabeth N Liao1, Aaliyah Riccardi1
1Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Summary
Financial conflicts of interest (FCOI) were associated with favorable publications on absorbable nasal valve implants. Many authors failed to disclose these financial conflicts, indicating a need for better reporting and review.
Area of Science:
- Otolaryngology
- Medical Ethics
- Publication Integrity
Background:
- Nasal valve collapse is a common condition requiring surgical intervention.
- Absorbable nasal valve implants offer a minimally invasive treatment option.
- The influence of financial interests on research outcomes requires careful examination.
Purpose of the Study:
- To investigate the association between author financial conflict of interest (FCOI) and the published stance on absorbable nasal valve implants.
- To assess the prevalence of FCOI among authors publishing on these devices.
Main Methods:
- Retrospective cross-sectional analysis of 12 US-based research publications (2016-2023) on absorbable nasal valve implants.
- Articles were categorized as favorable or neutral/unfavorable regarding implant outcomes.
- Author FCOI was determined through declared disclosures and the Centers for Medicare and Medicaid Services Open Payments Database.
Main Results:
- Favorable articles had a significantly higher proportion of authors with FCOI (82%) compared to neutral/unfavorable articles (18%).
- Undisclosed FCOI was prevalent in 50% of favorable articles versus 6% of neutral/unfavorable articles.
- Median author payments were substantially higher for favorable publications ($305,660 vs. $637).
Conclusions:
- Financial conflict of interest with manufacturers correlates with a favorable publication bias for absorbable nasal valve implants.
- The high rate of undisclosed FCOI necessitates improved author transparency and editorial oversight.
- Further research is warranted to ensure unbiased reporting in medical device literature.
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