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Updated: Feb 8, 2026

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
[Multilevel revision after complicated cataract surgery. Video article].
Paul Teping1, Berthold Seitz2, Loay Daas2
1Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes (UKS), Kirrberger Str. 100, Geb. 22, 66421, Homburg/Saar, Deutschland. paul.teping@uks.eu.
This study presents a single-stage surgical treatment for corneal decompensation caused by dislocated iris claw intraocular lenses (IOLs). The effective procedure involves IOL explantation, vitrectomy, secondary IOL implantation, and Descemet membrane endothelial keratoplasty (DMEK).
Area of Science:
- Ophthalmology
- Corneal Surgery
- Intraocular Lens Implantation
Background:
- Corneal endothelial decompensation and bullous keratopathy can result from dislocated anterior chamber iris claw intraocular lenses (IOLs).
- Current management often involves multiple surgical stages, increasing patient burden and risk.
Purpose of the Study:
- To evaluate the efficacy of a single-stage surgical revision for corneal decompensation secondary to iris claw IOL complications.
- To describe a novel surgical technique combining IOL explantation, vitrectomy, secondary IOL implantation, and Descemet membrane endothelial keratoplasty (DMEK).
Main Methods:
- A multi-stage surgical approach was employed, including IOL explantation via a sclerocorneal tunnel, complete pars plana vitrectomy, and secondary retroiridal iris claw IOL implantation.
- Simultaneous Descemet membrane endothelial keratoplasty (DMEK) was performed using a 7.5 mm donor graft via temporal access.
- The prerequisite for this procedure is the absence of pre-Descemet corneal scars.
Main Results:
- The described single-stage procedure effectively treats corneal endothelial decompensation and bullous keratopathy associated with dislocated iris claw IOLs.
- This combined approach offers a definitive solution in a single operative session.
Conclusions:
- IOL explantation combined with complete vitrectomy, secondary retroiridal iris-fixated IOL implantation, and DMEK is an effective and efficient single-stage treatment.
- This surgical strategy provides a viable option for managing complex cases of IOL-induced corneal pathology.
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