Related Experiment Video
Updated: Feb 8, 2026

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
Published on: July 26, 2024
Perinatal depression screening and diagnosis: Identifying opportunities to improve optimal care
Kelli Ryckman1,2, Maiti Peters3, Erik Parker4
1Indiana University Bloomington, Bloomington, United States. kryckman@iu.edu.
Insights
Racial and ethnic minorities are more likely to be screened for perinatal depression (PND) but less likely to be diagnosed. Targeted interventions are needed to address these screening and diagnosis disparities in PND.
Area of Science:
- Reproductive Health
- Mental Health
- Health Disparities
Background:
- Perinatal depression (PND) is a significant complication of pregnancy and postpartum periods, with severe consequences if untreated.
- PND affects a considerable number of women, necessitating effective screening and diagnostic strategies.
- Existing research indicates potential disparities in PND care, but a comprehensive examination is needed.
Purpose of the Study:
- To investigate racial, ethnic, and sociodemographic disparities in perinatal depression (PND) screening and diagnosis.
- To analyze screening and diagnosis patterns within a large Midwestern health system.
Main Methods:
- A multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) was employed.
- Electronic health records of 79,992 deliveries were analyzed.
- PND screening was identified via PHQ-9 or EPDS scores; diagnosis was confirmed using ICD-9/10 codes within one year of delivery.
Main Results:
- Older women (≥36 years) and women in rural areas were less likely to be screened for PND.
- Non-Hispanic Black, Hispanic, and Asian women were more likely to be screened but less likely to be diagnosed compared to Non-Hispanic White women.
- Public insurance enrollment correlated with higher PND diagnosis rates but not screening rates.
Conclusions:
- Significant disparities in PND screening and diagnosis persist.
- Racial and ethnic minority groups face inequities, being screened more but diagnosed less.
- Targeted interventions are crucial to address structural inequities and improve PND diagnosis for underserved populations.
Purpose:
Perinatal depression (PND), occurring during pregnancy or within the first year after childbirth, is a common medical complication with serious consequences when left untreated, including hospitalizations, increased morbidity, and suicide. This study examined the intersection among racial, ethnic, and sociodemographic disparities in PND screening and diagnosis within a Midwestern health system.
Methods:
We performed a multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) using electronic health record data for 79,992 deliveries. The study included women aged 15-50 who delivered live-born infants between 22 and 44 weeks of gestation. PND screening was identified by the presence of a PHQ-9 or EPDS score, and ICD9/10 codes were used to define depression diagnosis within one year before or after delivery.
Results:
Across groups older women (≥ 36 years) were less likely to be screened for PND (OR = 0.65; 95%CI = 0.56-0.75) but not less likely to be diagnosed. Non-Hispanic Black, Hispanic, and Asian women were more likely to receive PND screening (ORs = 1.23-1.31) but less likely to be diagnosed (ORs = 0.16-0.60) compared to Non-Hispanic White women. Enrollment in public insurance was not associated with PND screening but was linked to a higher likelihood of diagnosis (OR = 1.41, CI = 1.24-1.61). Women in rural areas were less likely to be screened for PND (OR = 0.66, CI = 0.58-0.75), with no significant association with diagnosis.
Conclusions:
Significant disparities exist in PND screening and diagnosis. Groups facing historic structural inequities are more likely to be screened but less likely to receive a diagnosis, highlighting the need for targeted interventions to address these inequities.
Related Concept Videos
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Freezing Point Depression and Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
Depressants
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Depression: Overview
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

