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Esophageal Perforation-I: Introduction

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....

Overview of Connective Tissues Proper

Overview of Connective Tissues Proper

Connective tissue proper is a class of connective tissue that encompasses all mature connective tissues except bone, cartilage, blood, and lymph. This extensive class of tissues has two subclasses — loose and dense connective tissues — classified based on the protein fiber arrangement and the amount of ground substance.
The loose connective tissues have a meshwork of thin collagen and elastin fibers, which provide tensile strength for support and enough elasticity to move...

Layers of Connective Tissue Proper

Layers of Connective Tissue Proper

Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing...

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:

Endoscopic Studies II: Thoracocentesis

Endoscopic Studies II: Thoracocentesis

Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...

Endoscopic Procedures I: Esophagogastroduodenoscopy

Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:

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Updated: Feb 8, 2026

Endoscopic Cholesteatoma Surgery

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Published on: January 19, 2022

How to properly treat endoscopic perforation.

Fengliang Dong¹, Jianwen Hu²

¹Department of Gastroenterology, Yiwu Tianxiang Medical Oriental Hospital, Yiwu, China.

|February 6, 2026

Summary

Appropriate treatment after endoscopic gastric perforation closure involves antibiotics based on patient symptoms. Early oral feeding can shorten hospital stays, while gastric tubes may increase discomfort.

Keywords:

abdominal pain antibiotics length of stay perforation

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Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy

Published on: August 22, 2025

Area of Science:

Gastroenterology
Endoscopic Surgery
Medical Treatment Efficacy

Background:

Endoscopic closure is a common treatment for gastric perforation.
Optimal post-procedure management strategies require further investigation.
Identifying factors influencing recovery is crucial for patient outcomes.

Purpose of the Study:

To evaluate treatment measures following endoscopic closure of gastric perforation.
To determine relationships between various interventions and patient outcomes (body temperature, abdominal pain, length of stay).

Main Methods:

Retrospective analysis of patients undergoing endoscopic closure of gastric perforation.
Statistical analysis to assess correlations between treatment factors (stomach tube, fasting time, antibiotics, tumor site, operation time, endoscopic method) and outcomes.

Main Results:

Body temperature correlated significantly with fasting time and antibiotics.
Abdominal pain incidence correlated significantly with gastric tube use, fasting time, and antibiotics.
Length of stay correlated significantly with fasting time, body temperature, and abdominal pain.

Conclusions:

Antibiotic use post-perforation repair should be guided by patient's abdominal pain and body temperature.
Gastric tubes may contribute to patient discomfort and abdominal pain.
Early oral feeding is recommended to reduce length of stay after endoscopic gastric perforation closure.