Intraocular pressure changes and pain scores within 24 hours and short-term outcomes after micropulse transscleral...

Area of Science:

• Ophthalmology
• Glaucoma Management
• Laser Therapy

Background:

• Glaucoma is a leading cause of irreversible blindness worldwide.
• Elevated intraocular pressure (IOP) is a primary risk factor for glaucoma progression.
• Effective IOP reduction strategies are crucial for preserving vision.

Purpose of the Study:

• To evaluate the efficacy of micropulse transscleral laser therapy (MP-TLT) in reducing intraocular pressure (IOP).
• To assess pain scores and short-term outcomes following MP-TLT.
• To analyze IOP changes over a 24-hour period and up to one week post-procedure.

Main Methods:

• A retrospective case series design was employed.
• MP-TLT was performed on 46 eyes of 40 patients, excluding those with prior cyclophotocoagulation or combined procedures.
• Intraocular pressure (IOP) and pain scores (NRS) were recorded serially up to 24 hours and at follow-up visits. Success was defined as ≥30% IOP reduction or IOP between 6-18 mmHg.

Main Results:

• Mean preoperative IOP was 40.6 mmHg, with a mean postoperative IOP of 24.5 mmHg (39.7% reduction) by the following day.
• Significant IOP reduction was observed at all measured time points (p < 0.05).
• The mean IOP reached 16.4 mmHg at week 1, with an 80.6% success rate at 12 months. Pain scores remained low throughout.

Conclusions:

• Micropulse transscleral laser therapy (MP-TLT) effectively reduces intraocular pressure (IOP) within 24 hours.
• The maximal IOP-lowering effect of MP-TLT is observed by one week post-procedure.
• MP-TLT demonstrates favorable short-term outcomes and a high success rate in glaucoma management.