Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hydration of Cement01:24

Hydration of Cement

953
Hydration of cement is a chemical reaction between cement particles and water. This process occurs primarily through two mechanisms: through-solution and topochemical. In the through-solution process, anhydrous compounds dissolve into their constituents, hydrates form in the solution, and then precipitate from the supersaturated solution. The topochemical process involves solid-state reactions at the cement particle surface. The through-solution process dominates the topochemical process at the...
953
Law of Segregation01:49

Law of Segregation

78.2K
When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
78.2K
Aqueous Solutions and Heats of Hydration02:42

Aqueous Solutions and Heats of Hydration

18.0K
Water and other polar molecules are attracted to ions. The electrostatic attraction between an ion and a molecule with a dipole is called an ion-dipole attraction. These attractions play an important role in the dissolution of ionic compounds in water.
When ionic compounds dissolve in water, the ions in the solid separate and disperse uniformly throughout the solution because water molecules surround and solvate the ions, reducing the strong electrostatic forces between them. This process...
18.0K
What is an Electrochemical Gradient?01:26

What is an Electrochemical Gradient?

128.1K
Adenosine triphosphate, or ATP, is considered the primary energy source in cells. However, energy can also be stored in the electrochemical gradient of an ion across the plasma membrane, which is determined by two factors: its chemical and electrical gradients.
The chemical gradient relies on differences in the abundance of a substance on the outside versus the inside of a cell and flows from areas of high to low ion concentration. In contrast, the electrical gradient revolves around an...
128.1K
Segregation in Fresh Concrete01:16

Segregation in Fresh Concrete

592
Segregation in fresh concrete is a phenomenon where the components of the concrete mix separate, leading to uneven distribution and compromised structural integrity. This separation typically occurs when concrete is subjected to excessive horizontal movement within forms, or when it is dropped from considerable heights or forced through narrow, winding paths. As a result, heavier coarse aggregate particles settle at the bottom, while lighter, finer materials such as cement and water rise to the...
592
What are Lipids?01:38

What are Lipids?

220.7K
Overview
220.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The temperature dependence of amyloid <i>β</i> solubility reveals the hydrophobic effect as the main driving force for fibril formation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Transient Interactions of α-Synuclein N- and C-Termini.

ACS chemical neuroscience·2026
Same author

Structural defects in amyloid-β fibrils drive secondary nucleation.

Nature communications·2026
Same author

Solubility and Metastability of the Amyloidogenic Core of Tau.

ACS chemical neuroscience·2026
Same author

A Bioinspired Mastoparan Exhibits Concentration-Dependent Anti-Bacterial Activity via Membrane Disruption.

ACS applied materials & interfaces·2025
Same author

Reduced protein solubility - cause or consequence in amyloid disease?

QRB discovery·2025
Same journal

Chemotactic self-organization captures the dynamics of mammalian hair follicle patterning.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Tomographic imaging of superconducting order using particle-hole interference.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Inhibitory potential of autologous neutralizing antibodies sets quantitative limits on the rebound-competent HIV-1 reservoir.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Inferring epidemiological parameters under an infectious phylogeography model with visitor dynamics.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Analytical modeling for suction cup designs for skin-interfaced wearable devices.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Improving cell-free metabolism through direct integration of artificial respiratory chains.

Proceedings of the National Academy of Sciences of the United States of America·2026
See all related articles

Related Experiment Video

Updated: Feb 8, 2026

Driving Under the Influence: How Music Listening Affects Driving Behaviors
07:25

Driving Under the Influence: How Music Listening Affects Driving Behaviors

Published on: March 27, 2019

13.1K

Hydration gradients drive lipid self-segregation.

Nikol Labecka1, Jenny M Andersson2, Emma Sparr1

  • 1Division of Physical Chemistry, Department of Chemistry, Lund University, Lund S-221 00, Sweden.

Proceedings of the National Academy of Sciences of the United States of America
|February 6, 2026
PubMed
Summary
This summary is machine-generated.

Evaporation creates hydration gradients, driving lipid segregation. Saturated lipids (DPPC) move to the interface, while unsaturated lipids (DOPC) move to hydrated regions, inverting proportions.

Keywords:
diffusio-osmosisevaporationnonequilibriumphospholipidself-assembly

More Related Videos

Tactile Vibrating Toolkit and Driving Simulation Platform for Driving-Related Research
07:15

Tactile Vibrating Toolkit and Driving Simulation Platform for Driving-Related Research

Published on: December 18, 2020

5.1K
Micro-drive Array for Chronic in vivo Recording: Drive Fabrication
14:03

Micro-drive Array for Chronic in vivo Recording: Drive Fabrication

Published on: April 20, 2009

25.9K

Related Experiment Videos

Last Updated: Feb 8, 2026

Driving Under the Influence: How Music Listening Affects Driving Behaviors
07:25

Driving Under the Influence: How Music Listening Affects Driving Behaviors

Published on: March 27, 2019

13.1K
Tactile Vibrating Toolkit and Driving Simulation Platform for Driving-Related Research
07:15

Tactile Vibrating Toolkit and Driving Simulation Platform for Driving-Related Research

Published on: December 18, 2020

5.1K
Micro-drive Array for Chronic in vivo Recording: Drive Fabrication
14:03

Micro-drive Array for Chronic in vivo Recording: Drive Fabrication

Published on: April 20, 2009

25.9K

Area of Science:

  • Soft matter physics
  • Biophysics
  • Physical chemistry

Background:

  • Evaporation of multicomponent aqueous mixtures creates gradients.
  • These gradients can influence the organization of other components, like lipids.
  • Phospholipids play crucial roles in biological membranes and soft matter systems.

Purpose of the Study:

  • To investigate how hydration gradients induced by evaporation affect the segregation of phospholipids.
  • To understand the role of lipid acyl chain saturation in this segregation process.
  • To develop a framework for predicting lipid organization in evaporating systems.

Main Methods:

  • High-resolution confocal Raman microscopy to resolve local composition.
  • Small- and wide-angle X-ray scattering to determine lamellar phases and structure.
  • Simultaneous measurement of composition and structure along the evaporation direction.

Main Results:

  • Evaporation-induced hydration gradients drive significant segregation between saturated (DPPC) and unsaturated (DOPC) phospholipids.
  • DPPC accumulates at the air-liquid interface, while DOPC is displaced to a more hydrated region.
  • The observed lipid distribution inverts initial proportions and is linked to the distinct water swelling capacities of DPPC (Lβ') and DOPC (Lα) phases.

Conclusions:

  • Hydration gradients are a robust driver of lipid segregation in evaporating soft matter.
  • The segregation phenomenon can be quantitatively described using equilibrium chemical potentials and multicomponent diffusion.
  • This work provides a general framework for predicting transport and organization in similar systems.