Related Experiment Video
Updated: Feb 8, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
Determinants and interrelations of exercise effects on sleep quality: A multimethod meta-analysis
Zhide Liang1, Shiao Zhao1, Shudong Tian2
1Faculty of Health Sciences and Sports, Macao Polytechnic University, Rua de Gomes, Macao, China.
Background:
This systematic review and Bayesian meta-analysis examined determinants of exercise effects on subjective sleep quality.
Methods:
We searched PubMed, Embase, Cochrane Library, Web of Science, Scopus and CINAHL from inception to August 2025 for randomised controlled trials in adults (≥18 years) comparing exercise with non-exercise controls. Two reviewers independently assessed risk of bias (RoB 2). Bayesian multilevel models, MetaForest and structural equation modelling estimated pooled effects and moderators, expressed as standardised mean differences (Hedges' g).
Results:
Two hundred trials (n = 23,523) were included. Compared with active controls, qigong, walking and high-intensity interval training showed the largest benefits. In 20 trials reporting objective sleep efficiency, exercise produced a small but significant improvement, consistent with subjective outcomes. Baseline sleep quality (assessed with Pittsburgh Sleep Quality Index) and population type were the main determinants of response. Populations with poorer baseline sleep quality were much more likely to achieve a clinically important improvement than good sleepers. Intervention duration showed a U-shaped association with benefit, peaking at 25 weeks. Certainty of evidence was very low.
Conclusion:
Exercise improves subjective sleep quality in a benefit-on-demand pattern, supporting prioritisation of approximately 25-week programmes for adults with moderate-to-severe sleep problems while acknowledging very low certainty.
Related Concept Videos
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Directing Effect of Substituents: meta-Directing Groups
Stages of Sleep
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Sleep Apnea
The condition is more prevalent among...
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

