Related Experiment Video
Updated: Feb 8, 2026

PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP
Published on: April 9, 2013
Contact-killing antimicrobial cationic starch/PBAT blown films: Physicochemical properties, antimicrobial mechanism,
Yuntong Wu1, Shan Gao1, Xiaolu Geng1
1College of Food Science and Engineering, Shandong Agricultural University, Engineering and Technology Center for Grain Processing of Shandong Province, Tai'an, Shandong Province, 271018, China.
Abstract:
Packaging materials with intrinsic antimicrobial activity can promote food safety and reduce preservatives reliance. Herein, cationic starch (CS) was blended with poly(butylene adipate-co-terephthalate) (PBAT) via extrusion blowing to fabricate composite films. Increasing CS proportions enhanced deformation resistance (69.42%), surface hydrophilicity (32.65%), moisture permeability (70.16%), as well as gas barrier (oxygen permeability reduced by 91.99% and carbon dioxide permeability by 98.48%). CS/PBAT films exhibited contact-killing bactericidal efficiencies of 98.04% and 89.65% against S. aureus and E. coli, respectively, and continuously inhibited their growth within 12-h test. Furthermore, CS/PBAT films showed solvent resistance within 21 days, and no CS migration was observed during 24-h contact on culture medium. Mechanistic studies revealed such effect derived from the electrostatic interactions between quaternary ammonium groups and bacterial membranes, which induced membrane disruption and cytoplasmic leakage. Comprehensive biocompatibility and safety assessment confirmed the biosafety of the films. CS/PBAT films prolonged the shelf life of refrigerated beef to 14 days, suppressing microbial growth, protein degradation, and lipid oxidation. This study offers a novel strategy for designing contact-killing packaging for food preservation.
More Related Videos
12:03Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
Published on: April 18, 2019
09:59Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
Published on: July 21, 2023
Related Concept Videos
Antimicrobial Effectiveness
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Factors Affecting Drug Biotransformation: Physicochemical and Chemical Properties of Drugs
The drug's acidity or basicity is essential in...
Cationic Chain-Growth Polymerization: Mechanism
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy