Related Experiment Video
Updated: Feb 8, 2026

Efficient Recombinant Parvovirus Production with the Help of Adenovirus-derived Systems
Published on: April 23, 2012
Decoding the parvovirus life cycle: Molecular mechanisms of cellular entry, trafficking, and replication
Aofei Yang1, Jian Chen1, Chengshui Liao1
1The Ministry of Education Key Laboratory for Animal Pathogens and Biosafety, Zhengzhou, 450000, Henan, China; College of Animal Science and Technology/Laboratory of Functional Microbiology and Animal Health, Henan University of Science and Technology, Luoyang, 471023, China; Luoyang Key Laboratory of Live Carrier Biomaterial and Animal Disease Prevention and Control, Henan University of Science and Technology, Luoyang, 471003, China.
None:
Parvoviruses exhibit a broad host spectrum and possess the potential of cross-species transmission. This evolutionary adaptability raises concerns regarding the potential expansion of their host range into human populations, thus posing a significant public health threat. This review systematically summarizes the current knowledge regarding the molecular interactions between parvoviruses and host cellular components, elaborating on the entire viral life cycle-encompassing cellular entry, intracellular trafficking, nuclear transport, DNA replication, and nuclear egress. It aims to lay a foundation for advancing research on parvovirus pathogenesis and identifying novel targets for vaccine and drug development.
Related Concept Videos
The Angiosperm Life Cycle
Retrovirus Life Cycles
Viral Replication: Lysogenic Cycle
Viral Replication: Lytic Cycle
Chromosome Replication
Half-life of a Reaction

