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Updated: Feb 8, 2026

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Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
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Multidisciplinary protocol and outcomes in placenta accreta spectrum: a 12 year cohort study
Ari Luder1,2, Elias Castel3,4, Nir Kleinmann5,4
1Department of Urology, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel. ari.luder@sheba.health.gov.il.
Archives of Gynecology and Obstetrics
|February 6, 2026
Summary
Implementing a multidisciplinary team (MDT) protocol significantly reduced complications for placenta accreta spectrum (PAS) surgery. This approach enhances patient safety in high-risk obstetric cases.
Area of Science:
- Obstetrics and Gynecology
- Surgical Management
- Patient Safety
Background:
- Placenta accreta spectrum (PAS) is a high-risk obstetric condition linked to hemorrhage, urologic injury, and hysterectomy.
- Increasing cesarean delivery rates correlate with rising PAS prevalence.
- Varied surgical approaches and limited multidisciplinary input may worsen maternal outcomes.
Purpose of the Study:
- To assess if a multidisciplinary team (MDT) protocol for PAS improves perioperative outcomes.
- To evaluate the impact of standardized care on surgical complications and patient recovery.
Main Methods:
- Retrospective cohort study of 417 women with PAS (2011-2022).
- Comparison of outcomes before (n=309) and after (n=108) implementing a structured MDT protocol in 2019.
- MDT protocol included standardized imaging, preoperative conferences, ureteral catheter placement, and on-site urologic support.
Main Results:
- MDT care was associated with significantly lower odds of urologic injury, surgical complications, transfusion, and hysterectomy.
- Adjusted estimated blood loss decreased by 260 mL, and length of hospital stay was reduced by 0.9 days.
- Findings were consistent in sensitivity analyses.
Conclusions:
- Implementation of an MDT protocol significantly reduced perioperative morbidity in PAS surgery.
- Multidisciplinary management represents a safer strategy for complex PAS cases.
- Standardized protocols enhance outcomes for high-risk obstetric conditions.
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