Broad functional landscape of geminivirus-encoded C4/AC4 protein
Yuzhen Mei1,2, Yaqin Wang1, Xueping Zhou3,4
1State Key Laboratory of Rice Biology and Breeding, Institute of Biotechnology, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
None:
Geminiviruses induce severe developmental abnormalities in crops and cause severe economic losses worldwide. Owing to the limited coding capacity of the viral genome, geminiviruses produce a limited number of multifunctional effectors to adapt to the host cellular environment. Among these effectors, the geminivirus-encoded C4/AC4 protein is a powerful viral effector with unexpected versatility. Here, we summarize the current knowledge on this remarkable protein and discuss future work on the C4/AC4 protein to provide new insights into plant-geminivirus interactions and integrated control of diseases induced by them.
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