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Summary
This summary is machine-generated.

Surface-guided radiotherapy (SGRT) offers superior accuracy and reproducibility for right-sided breast cancer radiotherapy positioning compared to traditional tattoos. This noninvasive method improves patient experience and treatment precision.

Keywords:
Breast cancerSGRTquality of liferadiotherapytattoo

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Area of Science:

  • Radiation Oncology
  • Medical Physics

Background:

  • Precise patient positioning is crucial for effective radiotherapy (RT) in right-sided breast cancer.
  • Conventional tattoo-based setups can cause patient distress and may lack precision.
  • Surface-guided radiotherapy (SGRT) presents a noninvasive alternative for patient alignment.

Purpose of the Study:

  • To compare the accuracy and reproducibility of SGRT versus conventional tattoo-based positioning for right-sided breast cancer RT.
  • To evaluate setup errors and inter-fraction variability between the two positioning methods.

Main Methods:

  • Prospective single-centre crossover study design.
  • Comparison of SGRT (AlignRT) and tattoo-based positioning in 52 patients.
  • Quantification of setup errors using cone-beam CT registrations and statistical analysis (Shapiro-Wilk, t-tests).

Main Results:

  • SGRT demonstrated significantly lower mean setup errors in all directions (longitudinal, vertical, lateral) compared to tattoo-based positioning (P < 0.001 for longitudinal and vertical, P = 0.044 for lateral).
  • SGRT exhibited reduced inter-fraction variability and fewer outliers (>1 cm).
  • Superior setup stability was observed with SGRT.

Conclusions:

  • SGRT with AlignRT provides enhanced accuracy and reproducibility for patient positioning in right-sided breast cancer radiotherapy.
  • This noninvasive method improves treatment precision, reduces setup variability, and enhances patient comfort by eliminating tattoos.
  • Further research is recommended to validate findings and assess long-term outcomes.