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Updated: Feb 10, 2026
An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Vaginal Reconstruction Using Urinary Bladder Tissue in a Patient with OEIS Complex: A Case Report
D R Winograd1, T L Wassmer1, M R Daugherty2
1Division of Pediatric & Adolescent Gynecology, Department of Surgical Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Background:
Omphalocele, cloacal exstrophy, imperforate anus, and spinal anomaly (OEIS) complex is a severe congenital defect that is associated with müllerian anomalies and duplicated external genitalia. The creation of a neovagina for these patients is dependent on the extent of congenital malformations, available native tissue, age at reconstruction, and presence of functional müllerian structures.
Case:
We present a patient diagnosed with OEIS with bilateral hemivaginas inserted into the bladder plate. We describe the use of urinary bladder tissue to separate the reproductive and urinary tracts, maintaining known patent müllerian systems.
Conclusion:
This case highlights a unique anomaly in which the bladder and hemivaginas are intimately connected, as well as the use of conveniently available urinary bladder tissue for the creation of a neovagina.
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