Opioid Stewardship
Alicia Agnoli1, Rebecca Hoss2, Mariya Kotova2
1Department of Family and Community Medicine, UC Davis, Sacramento, CA 95817, USA.
Primary Care
|February 8, 2026
Summary
This public health framework guides primary care opioid stewardship, focusing on safe prescribing and opioid use disorder treatment. It promotes collaborative care to reduce harm and improve patient outcomes.
Area of Science:
- Public Health
- Primary Care Medicine
- Pharmacology
Background:
- Opioid misuse and overdose present a significant public health crisis.
- Primary care settings are crucial for addressing opioid-related issues.
- Effective opioid stewardship is needed to mitigate risks and improve patient care.
Purpose of the Study:
- To present a public health-oriented framework for opioid stewardship in primary care.
- To outline evidence-based practices for safe opioid prescribing and management.
- To emphasize strategies for treating opioid use disorder within primary care.
Main Methods:
- Review of evidence-based practices for chronic pain management.
- Assessment of strategies for mitigating overdose risk.
- Guidelines for initiating buprenorphine treatment in primary care.
- Discussion of barriers like stigma and regulatory concerns.
- Emphasis on collaborative care models involving multidisciplinary teams.
Main Results:
- The framework integrates safe prescribing, risk assessment, and opioid use disorder treatment.
- Evidence supports managing chronic pain and reducing overdose risk through specific practices.
- Buprenorphine initiation in primary care is feasible and beneficial.
- Collaborative care models enhance the effectiveness of opioid stewardship.
- Addressing patient-centered care and reducing stigma are key components.
Conclusions:
- A comprehensive, patient-centered approach to opioid stewardship is vital in primary care.
- Integrating pharmacologic and non-pharmacologic strategies improves outcomes.
- Collaborative care models, including pharmacists and behavioral health specialists, are essential for reducing opioid-related harms.
- Overcoming barriers like stigma and regulatory fear is necessary for successful implementation.
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