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Updated: Feb 10, 2026

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
Published on: September 20, 2024
[Application of flavonoid in disease treatment based on multi-omics technologies]
Weihua Zhang1,2, Kezhen Han3,4, Kexin Zhao3,4
1Plateau Biomedical Big Data Mining and Bioinformatics Analysis Laboratory, Xizang Minzu University, Xianyang 712082. whzhang@xzmu.edu.cn.
Abstract:
Flavonoids are naturally occurring polyphenolic compounds widely distributed in nature, exhibiting pharmacological activities including anti-inflammatory effects and inhibition of cell proliferation. Their broader application has been constrained by unclear therapeutic targets. Recent advances in high-throughput sequencing and high-resolution mass spectrometry have elevated the importance of multi-omics analysis for elucidating flavonoid pharmacological effects, therapeutic targets, and regulatory networks. Integration of genomics, transcriptomics, proteomics, metabolomics, and metagenomics enables systematic characterization of flavonoid targets and modulation networks. Clarifying the application of multi-omics technologies in this field may support the clinical translation of flavonoids and provide new strategies for precision research in traditional Chinese medicine.
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