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Published on: December 20, 2024
Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype
Yue Gu1, Long-Lan Shu1, Tao Lu1
1Department of Otorhinolaryngology Upper Airway Inflammation and Tumor Laboratory, The First Affiliated Hospital of Chongqing Medical University Chongqing China.
None:
Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti-inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully integrating the underlying mechanisms with the clinical manifestations of AR. This review aims to summarize recent research findings on AR phenotypes and endotypes, enhance understanding of endotype-phenotype associations, and outline various treatment options based on phenotypes and endotypes to provide insights for early recognition and personalized clinical management of patients with AR.
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