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Updated: Feb 10, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Not just a goiter: Uncovering primary thyroid lymphoma
Venkata Kaumudi Ayaluri1, Angel Jose2, Harshitha Reddy3
1Department of Accident and Emergency, Clinical Fellow, Bronglais General Hospital, Aberystwyth, Wales, United Kingdom.
Primary thyroid lymphoma (PTL) is a rare, aggressive cancer. This case report details a 60-year-old woman diagnosed with PTL, emphasizing early diagnosis and treatment planning for this rapidly enlarging thyroid mass.
Area of Science:
- Oncology
- Hematology
- Endocrinology
Background:
- Primary thyroid lymphoma (PTL) is an uncommon and aggressive thyroid malignancy.
- It predominantly affects older women and can present as a rapidly growing neck mass.
Purpose of the Study:
- To report a case of primary thyroid lymphoma in a 60-year-old woman.
- To highlight the diagnostic challenges and therapeutic considerations for PTL.
Main Methods:
- Case presentation of a 60-year-old female with a progressively enlarging neck swelling.
- Diagnostic workup included imaging (ultrasound, CT scan), fine needle aspiration (FNA), and thyroid biopsy.
- Treatment involved standard chemotherapy (CHOP regimen).
Main Results:
- Imaging revealed an enlarged thyroid gland with surrounding soft tissue mass effect.
- FNA suggested a thyroid neoplasm with lymphoid cell predominance.
- Thyroid biopsy confirmed non-Hodgkin lymphoma of the thyroid.
Conclusions:
- PTL can present as a rapidly enlarging thyroid mass, posing a diagnostic challenge.
- Prompt diagnosis and a well-defined therapeutic plan are crucial for managing PTL.
- This case underscores the importance of considering PTL in the differential diagnosis of thyroid masses.
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