Related Experiment Video
Updated: Feb 10, 2026

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head
Published on: September 27, 2024
Managing medication-related osteonecrosis of jaw: A prospective observational study
Mahendra Kumar Dadarwal1, Timbadiya Vijaykumar Mansukhbhai2, Nishad Gawali3
1Department of Oral Surgery, Rajasthan Dental College, Jaipur, Rajasthan, India.
Abstract:
Medication-related osteonecrosis of the jaw (MRONJ) remains a significant clinical challenge due to its complex etiology and variable response to treatment. This prospective observational study evaluated the effectiveness of current management protocols in 130 patients receiving antiresorptive or antiangiogenic therapies. Patients were assessed clinically and radiographically and treated according to standardized stage-specific guidelines. Combined conservative and surgical interventions achieved better healing rates, symptom control, and improved quality of life over 12 months. These findings support ongoing refinement of stage-based MRONJ protocols to optimize therapeutic outcomes and patient care.
Related Concept Videos
Endocarditis III: Medical Management
Myocarditis III: Medical Management
Pericarditis III: Medical Management
Heart Failure V: Medical Management
Mitral Stenosis III: Medical Management
Aortic Regurgitation III: Medical Management

