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Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
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Serum calcium and magnesium in preeclampsia: A comparative study
Himanshy Rai1, Shweta Yadav1, Shambhavi Soni1
1Department of Obstetrics and Gynaecology, Government Medical College, Datia, Madhya Pradesh, India.
Bioinformation
|February 9, 2026
Summary
Preeclampsia is linked to lower serum calcium and magnesium levels. Screening for these electrolytes in pregnant women may help predict and prevent adverse outcomes like preterm birth.
Area of Science:
- Obstetrics and Gynecology
- Clinical Chemistry
Background:
- Preeclampsia is a serious hypertensive disorder of pregnancy.
- It is associated with endothelial dysfunction and electrolyte imbalances.
- Investigating mineral levels like calcium and magnesium is crucial.
Purpose of the Study:
- To evaluate serum calcium and magnesium levels in preeclamptic versus normotensive pregnant women.
- To assess the correlation between electrolyte levels and pregnancy complications.
Main Methods:
- A comparative study involving 100 preeclamptic and 100 normotensive pregnant women beyond 28 weeks gestation.
- Serum samples analyzed using spectrophotometry for calcium and magnesium concentrations.
Main Results:
- Significantly lower serum calcium levels (p<0.001) and magnesium levels (p=0.040) were observed in preeclamptic women.
- Preeclamptic group exhibited higher rates of preterm birth, cesarean delivery, and NICU admissions.
Conclusions:
- Lower serum calcium and magnesium may serve as indicators for preeclampsia.
- Electrolyte screening could aid in early risk stratification and management of preeclampsia complications.
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