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Multiple Hypertrophic Lichen Planus Mimicking Squamous Cell Carcinoma: A Case Report
Sho Hirata1, Daisuke Watabe1, Toshihide Akasaka2
1Department of Dermatology, Iwate Medical University School of Medicine, Yahabacho, Japan.
Case Reports in Dermatology
|February 9, 2026
Summary
Hypertrophic lichen planus (HLP) can mimic squamous cell carcinoma (SCC), leading to misdiagnosis. Careful clinicopathologic correlation is essential to distinguish HLP from SCC and avoid unnecessary treatments.
Area of Science:
- Dermatopathology
- Oncology
- Dermatology
Background:
- Hypertrophic lichen planus (HLP) with pseudoepitheliomatous hyperplasia (PEH) presents a diagnostic challenge.
- HLP can be misdiagnosed as well-differentiated squamous cell carcinoma (SCC).
- Fewer than 26 case reports document HLP initially misdiagnosed as SCC.
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