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Clinical, Pathological, and Imaging Study of Pilomatrixoma: A Retrospective Study
Qi Hao1,2, Cong-Gai Huang3,4, Chao-Ying Wu5
1Department of Orthopedics, The Affiliated Traditional Chinese Medicine Hospital Southwest Medical University Luzhou P.R. China.
Health Science Reports
|February 9, 2026
Summary
This study analyzed 471 pilomatrixoma cases, finding it most common in adolescents on the face and neck. Imaging and pathology aid diagnosis, with surgery as the primary treatment for this benign skin tumor.
Area of Science:
- Dermatology
- Pathology
- Radiology
Background:
- Pilomatrixoma is a benign skin appendage tumor.
- Understanding its clinical, pathological, and imaging features is crucial for diagnosis and management.
Purpose of the Study:
- To enhance clinicians' understanding of pilomatrixoma.
- To analyze the clinical, pathological, and imaging characteristics of pilomatrixoma.
Main Methods:
- Retrospective analysis of 471 pilomatrixoma cases.
- Inclusion of data from clinical, pathological, and imaging (ultrasonography, CT, MRI) assessments.
- Review of preoperative fine needle aspiration results.
Main Results:
- Pilomatrixoma predominantly affects females (52.4%) and occurs most frequently in children aged 0-10 years (46.5%).
- The most common locations are the face (especially the parotid region) and neck.
- Histopathology reveals basaloid and shadow cells; imaging shows calcifications, specific echo patterns on ultrasound, and characteristic findings on CT and MRI.
Conclusions:
- Pilomatrixoma is common in adolescent females, typically on the face and neck.
- Cytopathology and imaging provide diagnostic clues, while histopathology confirms the diagnosis.
- Complete surgical resection remains the treatment of choice.
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