Related Experiment Video
Updated: Feb 10, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Large Inferior Rectus Recession without Lower Eyelid Retraction in Thyroid Eye Disease
Birsen Gokyigit1, Asli Inal2, Ceren Gurez2
1Department of Ophthalmology, Private practice, Istanbul, Türkiye.
Objectives:
In this study, a new technique that does not cause lower eyelid retraction in patients with excessive limitation of movement and vertical strabismus due to inferior rectus (IR) fibrosis in thyroid eye disease was introduced.
Methods:
There were six patients with their six eyes with their mid-term results.
Operation Technique:
According to the deviation amount, a 7-14 mm length bovine pericardium (Tutopatch®) was inserted between the distal end of the tendon and the beginning of the muscle fibers, which are located between the tendon's distal end and the tendon muscle junction to the IR with 6/0 non-absorbable suture.
Results:
There were six cases with a mean 19.5±5.2 PD (PD: prism diopters) (14-26 PD) vertical deviation and severe up-gaze limitations with a mean -4.1±0.75. The post-operative vertical deviation was a mean of 3.5±1.22 PD, and the limitation of upgaze was a mean of -1.3±0.4.
Conclusion:
This procedure provides effective results in reducing gaze limitation and vertical deviation in thyroid patients without causing any problems in the eyelids.
Related Concept Videos
Clot Retraction and Fibrinolysis
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Muscles of the Eye
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
Accessory Structures of the Eye

