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Primary Peritoneal Carcinomatosis: A Case Report

Anvitha Soundararajan¹, Rodrigo Furlan Silva Fabri¹, Barney Soskin¹

¹Internal Medicine, Texas Tech University Health Sciences Center El Paso, Paul L. Foster School of Medicine, El Paso, USA.

|February 9, 2026

Abstract:

Primary peritoneal adenocarcinoma (PPC) is an uncommon malignancy that arises from the peritoneal lining and shares striking clinical, histopathological, and immunophenotypic similarities with epithelial ovarian carcinoma (EOC). Because both entities derive from Müllerian epithelium, distinguishing PPC from metastatic ovarian or gastrointestinal carcinoma poses a significant diagnostic challenge, particularly in the absence of detectable ovarian masses. Recognizing this rare entity is clinically relevant, as accurate classification influences prognosis, genetic counseling, and management strategies.

Keywords:

adenocarcinoma ascites immunohistochemistry müllerian carcinoma ovarian cancer mimic peritoneal carcinomatosis primary peritoneal carcinoma

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Keywords:

adenocarcinoma ascites immunohistochemistry müllerian carcinoma ovarian cancer mimic peritoneal carcinomatosis primary peritoneal carcinoma

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