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Related Concept Videos

Variation: Normal Distribution, Range, and Standard Deviation02:32

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In the field of psychology, there are several ways to organize measurements of a trait, feature, or characteristic (i.e., variables). Qualitative data, such as ethnicity, can be tabulated into a frequency count to provide information about the proportion, as well as the variety of groups in a sample or population. On the other hand, researchers can perform a wider set of calculations on quantitative data. The mean, mode, and median, for instance, are central tendency measures to identify a...
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Apart from the measures of central tendency, distribution, outliers, and the changing characteristics of data with time, an important characteristic of any data set is its variation or spread. In some data sets, the data values are concentrated closely near the mean; in others, the data values are more widely spread out from the mean.
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The mean absolute deviation is also a measure of the variability of data in a sample. It is the absolute value of the average difference between the data values and the mean.
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Variation in and deviation from protective ventilation during lung surgery.

Matthew C So1, Camila Machado de Souza2, Gordon Buduhan3

  • 1Department of Radiology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

JTCVS Techniques
|February 9, 2026
PubMed
Summary

Lung-protective ventilation during one-lung ventilation (OLV) is crucial for reducing postoperative pulmonary complications (PPCs). Adherence to protective strategies was low, and higher peak inspiratory pressures during OLV were linked to increased PPCs.

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Area of Science:

  • Anesthesiology
  • Thoracic Surgery
  • Critical Care Medicine

Background:

  • One-lung ventilation (OLV) is standard for lung resections, necessitating protective ventilation to minimize lung injury.
  • Postoperative pulmonary complications (PPCs) are a significant concern following lung surgery.
  • Understanding ventilatory strategies during OLV is key to improving patient outcomes.

Purpose of the Study:

  • To describe current ventilatory strategies during OLV.
  • To identify factors influencing these strategies.
  • To investigate the association between OLV ventilation and PPCs.

Main Methods:

  • Prospective cohort study of 225 patients undergoing lung surgery.
  • Real-time intraoperative ventilation data collection.
  • Assessment of PPCs using the Ottawa Thoracic Morbidity and Mortality classification.
  • Statistical analysis including multivariable regression.

Main Results:

  • Median tidal volume was 6.4 mL/kg, with only 7.5% of surgeries meeting the <5 mL/kg VT target.
  • High adherence (86.7%) to PEEP ≥5 cmH2O was observed.
  • Increased peak inspiratory pressure and longer OLV duration were significantly associated with PPCs.

Conclusions:

  • Adherence to lung-protective ventilation during OLV remains suboptimal.
  • Elevated peak inspiratory pressure during OLV is a significant risk factor for PPCs.
  • Targeting peak inspiratory pressure reduction is a critical area for quality improvement and knowledge translation.