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Related Experiment Video

Updated: May 5, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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"Head First" approach streamlines aortic arch replacement.

Bo Chang Brian Wu1,2, Drake S Rosenberg2, Meghan Skalicky2

  • 1Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colo.

JTCVS Techniques
|February 9, 2026
PubMed
Summary
This summary is machine-generated.

The "Head First" graft technique shows acceptable outcomes for complex aortic arch repair, prioritizing cerebral protection and efficient reconstruction. This method may improve technical feasibility in aortic replacement surgeries.

Keywords:
Head First graftaortic arch replacementcerebral protectionstroketrifurcated graft

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Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Vascular Surgery

Background:

  • The "Head First" graft technique is increasingly favored for aortic replacement.
  • Evaluating its safety and efficacy in complex aortic arch repair is crucial.

Purpose of the Study:

  • To assess the performance and safety of the "Head First" technique in zone 2 or more extensive aortic arch replacement.
  • To focus on operative efficiency, cerebral protection, and outcomes in open arch repair.

Main Methods:

  • Retrospective review of 150 patients undergoing "Head First" aortic arch repair (August 2020 - March 2025).
  • Comparison of perioperative variables between acute type A aortic dissection and elective repair groups.
  • Logistic regression analysis to identify stroke risk factors.

Main Results:

  • Overall disabling stroke rate was 10.7%, and 30-day mortality was 16.7%.
  • Patients with acute type A aortic dissection experienced longer bypass and circulatory arrest times but similar stroke rates compared to elective cases.
  • Male gender was found to be independently protective against stroke.

Conclusions:

  • The "Head First" approach offers acceptable outcomes for complex aortic arch replacement.
  • It facilitates effective cerebral protection and efficient reconstruction, potentially improving technical feasibility.