Repair of Partial and Transitional Atrioventricular Septal Defects: Mid-term Outcomes in a Single-center Cohort
Zewen Chen1, Yifan Li2, Wen Xie3
1Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510080 Guangzhou, Guangdong, China.
Reviews in Cardiovascular Medicine
|February 9, 2026
Summary
Surgical repair of atrioventricular septal defects (AVSDs) shows excellent mid-term survival and low reoperation rates in pediatric and adult patients. Refined atrioventricular valve repair strategies are crucial for reducing reinterventions.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Atrioventricular septal defects (AVSDs) are complex congenital heart conditions.
- Surgical repair aims for optimal outcomes and minimal reintervention.
- Evaluating mid-term results of AVSD repair in diverse age groups is critical.
Purpose of the Study:
- To assess the mid-term outcomes of surgical repair for partial and transitional atrioventricular septal defects (AVSDs).
- To compare outcomes between pediatric and adult patient populations.
- To analyze reoperation rates and atrioventricular valve (AVV) repair strategies.
Main Methods:
- Retrospective review of 136 patients undergoing partial or transitional AVSD repair (Jan 2019 - Dec 2022).
- Assessment of mortality, reoperation, and AVV repair strategies.
- Follow-up included evaluation of left atrioventricular valve (LAVV) regurgitation.
Main Results:
- No early or late deaths occurred in 136 patients (median follow-up 50.5 months).
- A low reoperation rate of 2.9% was observed, primarily for LAVV issues.
- Reoperation rates and LAVV regurgitation did not significantly differ by AVSD subtype, age, or annuloplasty type.
Conclusions:
- Surgical repair of partial and transitional AVSDs yields excellent mid-term survival and low reoperation rates.
- Refinement of AVV repair is essential to minimize LAVV reintervention and prevent outflow tract obstruction.
- Long-term follow-up is necessary to assess the durability of annuloplasty techniques.
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