Related Experiment Video

Updated: Feb 10, 2026

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
08:00

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

Published on: June 15, 2015

14.5K

Repair of Partial and Transitional Atrioventricular Septal Defects: Mid-term Outcomes in a Single-center Cohort

Zewen Chen1, Yifan Li2, Wen Xie3

  • 1Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 510080 Guangzhou, Guangdong, China.

Reviews in Cardiovascular Medicine
|February 9, 2026
PubMed

Insights

Surgical repair of atrioventricular septal defects (AVSDs) shows excellent mid-term survival and low reoperation rates in pediatric and adult patients. Refined atrioventricular valve repair strategies are crucial for reducing reinterventions.

Area of Science:

  • Cardiovascular Surgery
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Atrioventricular septal defects (AVSDs) are complex congenital heart conditions.
  • Surgical repair aims for optimal outcomes and minimal reintervention.
  • Evaluating mid-term results of AVSD repair in diverse age groups is critical.

Purpose of the Study:

  • To assess the mid-term outcomes of surgical repair for partial and transitional atrioventricular septal defects (AVSDs).
  • To compare outcomes between pediatric and adult patient populations.
  • To analyze reoperation rates and atrioventricular valve (AVV) repair strategies.

Main Methods:

  • Retrospective review of 136 patients undergoing partial or transitional AVSD repair (Jan 2019 - Dec 2022).
  • Assessment of mortality, reoperation, and AVV repair strategies.
  • Follow-up included evaluation of left atrioventricular valve (LAVV) regurgitation.

Main Results:

  • No early or late deaths occurred in 136 patients (median follow-up 50.5 months).
  • A low reoperation rate of 2.9% was observed, primarily for LAVV issues.
  • Reoperation rates and LAVV regurgitation did not significantly differ by AVSD subtype, age, or annuloplasty type.

Conclusions:

  • Surgical repair of partial and transitional AVSDs yields excellent mid-term survival and low reoperation rates.
  • Refinement of AVV repair is essential to minimize LAVV reintervention and prevent outflow tract obstruction.
  • Long-term follow-up is necessary to assess the durability of annuloplasty techniques.
Abstract

Keywords:
atrioventricular valve regurgitationpartial atrioventricular septal defectreoperationring annuloplastysurgical outcomestransitional atrioventricular septal defect

More Related Videos

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse08:19

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

Published on: December 16, 2022

2.4K
Myocardial Infarction and Functional Outcome Assessment in Pigs12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.7K

Related Concept Videos

Phase Transitions02:31

Phase Transitions

Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
23.3K
Properties of Transition Metals02:58

Properties of Transition Metals

Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
30.0K
Phase Transitions: Melting and Freezing02:39

Phase Transitions: Melting and Freezing

Heating a crystalline solid increases the average energy of its atoms, molecules, or ions, and the solid gets hotter. At some point, the added energy becomes large enough to partially overcome the forces holding the molecules or ions of the solid in their fixed positions, and the solid begins the process of transitioning to the liquid state or melting. At this point, the temperature of the solid stops rising, despite the continual input of heat, and it remains constant until all of the solid is...
15.2K
Phase Transitions: Sublimation and Deposition02:33

Phase Transitions: Sublimation and Deposition

Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
20.3K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
8.8K
Mismatch Repair01:36

Mismatch Repair

Overview
43.7K