Related Experiment Video
Updated: Feb 10, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Saving the split: An umbrella review on therapeutic approaches for cracked tooth syndrome
Supreet Kaur1, Lakshmi Puzhankara2, Neetha Shenoy1
1Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Introduction:
Cracked tooth syndrome (CTS) has become a therapeutic dilemma due to a lack of consolidated evidence guiding its management. This umbrella review synthesized evidence from published systematic reviews of therapeutic interventions in CTS.
Methods:
The protocol was registered in PROSPERO (CRD420250648720), and it was conducted according to PRISMA 2020 guidelines. The searches were conducted up to June 15, 2025, in PubMed, Cochrane Library, Scopus, and EMBASE. Two reviewers screened and extracted data independently. A Measurement Tool to Assess Systematic Reviews 2 was used to measure methodological quality, and a citation matrix and Corrected Covered Area (CCA) to measure overlap of primary studies.
Results:
Ten systematic reviews were identified, and four of them satisfied the inclusion criteria; they included 30 separate primary studies (45 study entries). The CCA was 17%, indicating high overlap. Endodontic therapy followed by full cuspal coverage demonstrated the highest prognosis with 84%-96% survival, 82%-84% success rate, and a lower chance of extraction by 11.3 times. On the other hand, there was an association of noncrowned teeth with pulpal problems, failure of restoration, and recurring symptoms, particularly in the presence of deep periodontal pockets.
Conclusion:
Endodontic therapy followed by full cuspal coverage provides the most predictable outcome in CTS. More evidence ought to be augmented using standardized measures, patient-reported outcomes, and cost-effectiveness calculations.
Related Concept Videos
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Types of Non-structural Cracks in Concrete
Plastic shrinkage cracks typically form within hours after the concrete is poured. The concrete's surface dries faster than the bottom, creating tensile stress that the still-plastic concrete cannot withstand, leading to diagonal or randomly patterned cracks on the concrete surface.
¹H NMR: Complex Splitting
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied...
Therapeutic Index

