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Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay
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Development and Design of a Pediatric Case-Based Virtual Escape Room on Acute Iron Toxicity
Kaitlyn Boggs1, Manu Madhok2, Tania Ahluwalia3
1Medical University of South Carolina, Division of Pediatric Emergency Medicine, Charleston, SC.
Journal of Education & Teaching in Emergency Medicine
|February 9, 2026
Summary
Virtual escape rooms effectively teach acute iron toxicity to medical trainees. This gamified approach fosters teamwork and is adaptable for both online and in-person learning environments.
Area of Science:
- Medical Education
- Toxicology
- Gamification
Background:
- Acute iron toxicity is a significant concern in children, with nearly 11,000 cases reported annually in the US.
- Iron tablets, especially those containing ferrous sulfate, pose a risk due to their appealing appearance and high elemental iron concentration.
- Virtual escape rooms (VERs) offer an innovative, gamified approach to medical education, allowing remote collaboration.
Purpose of the Study:
- To evaluate the effectiveness of a virtual escape room (VER) as a didactic tool for teaching acute iron toxicity.
- To assess the VER's impact on teamwork and its adaptability across different educational settings and platforms.
Main Methods:
- A seven-step development process was used to create the VER, aligning puzzles with learning objectives.
- The VER was hosted on Articulate 360, supported by a facilitator guide.
- Implementation involved pre-briefing, a timed escape room scenario, debriefing, and post-evaluation surveys, conducted both in-person and online.
Main Results:
- 55 respondents completed post-evaluation surveys.
- A high percentage of trainees and faculty found the VER design easy to follow (78.2%), fostered teamwork (90.9%), and considered it a feasible educational method (85.5%).
Conclusions:
- The virtual escape room (VER) is a successful and versatile educational tool for acute iron toxicity.
- The VER format is adaptable for various learners (trainees, faculty, nursing) and delivery methods (in-person, online).
- Future research should focus on long-term outcome data and knowledge retention in clinical management.
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