Related Experiment Video
Updated: Feb 10, 2026
10:21
Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive
Published on: July 4, 2007
11.1K
Consensus Building on Strategies That Address Medical Mistrust to Better Engage Priority Populations in HIV Cure
Anastasia Korolkova1, Elizabeth Nguyen2, Ali Ahmed1
1Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego.
Behavioral Medicine (Washington, D.C.)
|February 9, 2026
Summary
Building trust is key for HIV cure research participation. Connecting potential participants with current trial members and active listening emerged as top strategies to overcome medical mistrust.
Area of Science:
- Medical research ethics
- Public health initiatives
- HIV/AIDS research
Background:
- Medical mistrust significantly hinders diversity in HIV cure-related clinical trials.
- Addressing this mistrust is crucial for advancing HIV cure research in the United States.
Purpose of the Study:
- To identify and rank strategies for overcoming medical mistrust to enhance participation in HIV cure research.
- To build consensus among diverse experts on effective engagement methods.
Main Methods:
- A hybrid Delphi consensus-building process was employed with 54 multidisciplinary experts.
- Experts completed three rounds of surveys, ranking qualitative strategies identified in initial qualitative responses.
- Panelists represented various stakeholder groups, including community members, researchers, clinicians, and ethicists.
Main Results:
- The highest-ranked strategy involved connecting eligible participants with current or former HIV cure trial participants to share experiences.
- Active listening to address participant questions and concerns was also a top-ranked strategy for building trust.
- While overall consensus was reached, slight variations in rankings were observed among different expert groups.
Conclusions:
- Prioritizing peer-to-peer interactions and empathetic communication can effectively mitigate medical mistrust.
- These strategies are vital for promoting broader and more equitable participation in novel HIV cure research.
Related Concept Videos
01:25Strategies for Assessing and Addressing Confounding
420
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
420
02:04Conservation of Small Populations
17.4K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.4K
01:20Curing of Concrete
369
The hydration of cement takes place within the water-filled capillary pores. However, environmental elements can disrupt this process by evaporating water from the concrete surfaces. Sealed concrete with a water-cement ratio below 0.5 experiences self-desiccation, leading to water loss. The water loss in concrete is mitigated by curing. This technique involves keeping the concrete saturated to maintain the necessary temperature and moisture conditions, to optimally fill the spaces in the cement...
369
01:26Curing Methods
306
Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...
306
01:25Accelerated Curing of Concrete
484
Accelerating concrete curing is achieved by applying heat and additional moisture. This process accelerates the hydration of the cement, resulting in an earlier strength gain in the concrete. Steam curing is a method wherein the concrete products are either transported through a chamber on a conveyor belt or encased in plastic, allowing steam at atmospheric pressure to circulate freely around them. This process begins with a phase of moist curing that typically lasts between 3 to 5 hours, after...
484
01:25What is Population Genetics?
64.9K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.9K