Selective corneal wavefront-guided and wavefront-optimized myopic LASIK using high-repetition-rate excimer laser:...

Area of Science:

• Ophthalmology
• Refractive Surgery
• Corneal Surgery

Background:

• Laser-assisted in situ keratomileusis (LASIK) is a common refractive surgery.
• Higher-order aberrations (HOAs) can impact visual quality after LASIK.
• Corneal wavefront-guided (CW) ablation aims to correct HOAs, while aberration-free (AF) profiles focus on refractive correction.

Purpose of the Study:

• To compare refractive, visual, and HOA outcomes of CW versus AF ablation profiles in LASIK.
• To evaluate the safety and efficacy of these ablation profiles using a high-repetition-rate excimer laser.

Main Methods:

• Retrospective study of 85 patients undergoing myopic LASIK.
• Contralateral eyes treated with either CW or AF ablation profiles using the AMARIS 1050RS excimer laser.
• CW ablation targeted specific HOAs (vertical/horizontal coma, spherical aberration) above a threshold.

Main Results:

• Postoperative astigmatism and visual acuity were similar between CW and AF groups.
• The CW group showed a more hyperopic shift (0.18 D overall, 0.26 D in SA subgroup) compared to the AF group.
• CW ablation resulted in less HOA induction or greater HOA reduction than AF ablation.

Conclusions:

• Both CW and AF LASIK using the AMARIS 1050 RS are safe and provide satisfactory visual outcomes.
• CW ablation is more effective in managing HOAs compared to AF ablation.
• A hyperopic shift is associated with CW ablation when treating spherical aberration.