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Postoperative chyle leak after pancreatic surgery: scoping review
Artur Rebelo1, Enzo Rauchbach2, Jörg Kleeff1,2
1Department of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Halle, Germany.
Chyle leak remains a significant complication after pancreatic surgery, with an overall incidence of 8.0%. Robotic and open pancreatoduodenectomy show no significant difference in chyle leak rates.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Chyle leak is a serious complication following pancreatic resection, impacting patient morbidity and mortality.
- Existing data on chyle leak incidence, risk factors, and treatment are inconsistent.
- Robotic pancreatic surgery is perceived to reduce complications compared to open procedures.
Purpose of the Study:
- To evaluate the incidence and risk factors of chyle leak after pancreatic resection.
- To compare chyle leak rates between open and robotic pancreatic surgery.
- To review therapeutic strategies for managing chyle leak.
Main Methods:
- A comprehensive scoping literature review was performed.
- Searched multiple databases for studies on open or robotic pancreatic resection with chyle leak.
- Included studies defined chyle leak per the International Study Group on Pancreatic Surgery criteria.
Main Results:
- Analyzed 58 studies (30,039 patients) from 2007-2025.
- Pooled incidence of chyle leak after pancreatic resection was 8.0%.
- Incidence varied by procedure: 9.5% (partial pancreatoduodenectomy) to 1.7% (enucleation).
- Comparative studies showed 10% chyle leak for robotic vs. 12% for open pancreatoduodenectomy.
Conclusions:
- Chyle leak is a substantial risk following pancreatic resection.
- Surgical technique advancements have not eliminated this complication.
- No significant difference in chyle leak rates between robotic and open pancreatoduodenectomy was observed.
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